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Sunday, April 19, 2020 | History

6 edition of Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy found in the catalog.

Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy

  • 184 Want to read
  • 6 Currently reading

Published by Springer .
Written in English

    Subjects:
  • Medical / Nursing,
  • Science/Mathematics,
  • Mechanism of action,
  • Cancer Chemotherapy,
  • Medical,
  • Organoplatinum compounds,
  • Oncology,
  • Immunology,
  • Life Sciences - Biochemistry,
  • Cancer,
  • Medical / Oncology,
  • Medical-Immunology,
  • Neoplasms,
  • Science-Life Sciences - Biochemistry,
  • Cisplatin,
  • Antineoplastic agents,
  • Congresses

  • The Physical Object
    FormatHardcover
    Number of Pages564
    ID Numbers
    Open LibraryOL9698785M
    ISBN 10030644027X
    ISBN 109780306440274

    Full Description:" International Platinum Conference 'Platinum Adding Value' gives motivation to analyze information and is also useful when criticizing plots; or it is a well-written section if the character is properly designed, if the narrative sounds innocent, etc. If you ever have the opportunity to discuss the book with others, you will be able to clearly tell their views, as you . Abstract. The history of medicine shows that metal compounds have been extensively used in medical therapy. For example, antimony compounds were used as emetics and in tropical disease treatment, whereas bismuth compounds were widely applied as astringents and dermatological : Smiljko Ašperger.


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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy by Stephen B. Howell Download PDF EPUB FB2

The 7th International Symposium on Platinum and other metal coordination compounds in Cancer Chemotherapy, ISPCC '95, organized by the European Cancer Centre, was held in Amsterdam, the Netherlands, MarchAuthor: Steef van de Velde. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy: Medicine & Health Science Books @ Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy (Developments in Oncology): Medicine & Health Science Books @.

Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy Proceedings of the Fifth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy Abano, Padua, ITALY — June 29–July 2, Editors: Nicolini, Marino (Ed.) Free Preview.

" Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications ", edited by Andrea Bonetti, Steve B.

Howell, Roberto Leone, and Franco Muggia, provides succinct summaries of the major new developments in field of platinum drug therapy drawn from presentations made at the 10 th International Symposium Price: $ Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy Proceedings of the Fifth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy Abano, Padua, ITALY - June 29–July 2, It was a great pleasure and honour to have been invited to attend this Seminar and to present a final impression.

The association in this field between the Chester Beatty Research Institute and Dr. Rosenberg's School at East Lansing is something which I. Platinum and other metal coordination compounds in cancer chemotherapy. A commentary on the sixth international symposium: San Diego, California, th January Cited by: Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy held at San Diego, California from th Januaryover 50 invited lectures and over posters were presented.

Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a tumor cell's resistance to platinum compounds. Inhibition of this repair system by combination chemotherapy with the excision repair inhibitors HU and Ara-C produces synergistic cell kills and increased levels and persistance of DNA interstrand crosslinks.

Synthesis and Activity of Platinum Compounds NMR Spectroscopy of Platinum Drugs: From DNA to Body Fluids Kevin J. Barnham, Susan J. Berners-Price, Zijian Guo, Piedad del Socorro Murdoch, Peter J. Sadler. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2.

Editors: van de Velde, Steef, Schornagel, J.H. (Eds.) Free Preview. Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a tumor cell's resistance to platinum compounds.

Inhibition of this repair system by combination chemotherapy with the excision repair inhibitors HU and Ara-C produces synergistic cell kills and. This is the Tenth Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, and its highlights provide further confirmation of the value of scientific investment in this.

Platinum Coordination Complexes in Cancer Chemotherapy. Proceedings of the Fourth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy book Coordination Complexes in Cancer Chemotherapy convened in Burlington, Vermont by the Vermont Regional Cancer Center and the Norris Cotton Cancer Center, June 22–24, The idea for convening a Fourth International Symposium on Platinum Coordination Complexes in Cancer Chemotherapy was born in an assembly of researchers from the Vermont Regional Cancer Center and the Norris Cotton Cancer Center who shared a common interest in metal Author: Miles P.

Hacker. Platinum Coordination Compounds in Cancer Chemotherapy Article in Critical Reviews in Oncology/Hematology 53(1) January with 26 Reads How we measure 'reads'. Platinum and other metal coordination compounds in cancer chemotherapy. A commentary on the sixth international symposium: San Diego, California, th January Coordination Chemistry Reviews, 12 () Elsevier Scientific Publishing Company, Amsterdam Printed in The Netherlands TRANSITION METAL COMPLEXES IN CANCER CHEMOTHERAPY M J.

CLEARE Johnson Matthey & Co, Ltd, Research Laboratories, Wembley, Middlesex (Great Britain) (Received July 9th, ) CONTENTS A Introduction Cited by: • First, classical platinum-based complexes, cis-platin and platinum (IV) complexes are extensively reviewed.

• Complexes of ruthenium, gold, silver, copper, iron, cobalt gallium, rhodium titanium, arsenic, and antimony are also discussed. • Perspectives of the coordination compounds use in cancer are by: "The 7th International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, ISPCC '95, organized by the European Cancer Centre, was held in Amsterdam, the Netherlands, March"--Preface.

Get this from a library. Platinum and other metal coordination compounds in cancer chemotherapy: proceedings of the Fifth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, Abano Padua, Italy, June July 2, [Marino Nicolini;].

"Proceedings of the Sixth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, held January, in San Diego, California"--Title page verso.

Platinum compounds. The platinum compounds are largely used in the treatment of lung, breast, ovarian, and colon cancers. The chemotherapeutic mechanism of platinum compounds is typical of DNA-binding alkylating agents.

If the DNA damage exceeds the ability of the cell to repair, the cell undergoes apoptotic cell death. ISBN: X: OCLC Number: Notes: "The 7th International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, ISPCC '95, organized by the European Cancer Centre, was held in Amsterdam, the Netherlands, March"--Preface.

1. Introduction. Platinum compounds constitute one of the most widely used classes of anti-cancer drugs. Approximately half of all cancer patients receiving chemotherapy are treated with cisplatin, carboplatin or oxaliplatin (figure 1).Testicular cancer responds particularly well to cisplatin treatment and, following introduction of this drug into clinical use, Cited by: The application of platinum compounds in cancer therapy was one of the most unexpected developments in pharmaceuticals in the last 50 years.

Many reviews have been published previously on this topic; in this journal the most recent being by Reedijk in ().The potential of platinum compounds was discovered by Rosenberg in ().He had recently taken up an. Platinum and other metal coordination compounds in cancer chemotherapy.

A commentary on the sixth internationa l symposium: San Diego, California, 23. Platinum compounds have been used in the treatment of several human tumors including testicular, bladder, lung, head and neck, and cervical cancer.

The disadvantages of currently marketed platinum analogues are that they must all be administered via intravenous by: "Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications", edited by Andrea Bonetti, Steve B.

Howell, Roberto Leone, and Franco Muggia, provides succinct summaries of the major new developments in field of platinum drug therapy drawn from presentations made at the 10th International. Platinum And Other Metal Coordination Compounds In Cancer Chemotherapy 2 V 2 Kindle Ebook - J.

Rowling Publishing The 7th International Symposium On Platinum And Other Metal Coordination Compounds In Cancer Chemotherapy Ispcc 95 Organized By. Cisplatin and the Structure–Activity Relationships.

The preparation of a coordination complex with the simple formula cis-[Pt(NH 3) 2 Cl 2] was first described by Peyrone in the mid th century and, as was often the custom at the time, the compound came to bear his name as Peyrone’s chloride ().The discovery of the antineoplastic properties of this complex by Barnett Cited by: Sixth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, San Diego, California, USA (23–26 January ) Google Scholar Cited by: Chemotherapy in Prague in Both meetings were, however, preliminary inas- much as clinical studies of the platinum compounds were only just beginning.

The Second International Symposium on Plati- num Coordination Complexes in Cancer Chemotherapy, held at Wadham College, Oxford in April, devoted one day to the.

Nevertheless, platinum-based cancer therapy remains a topic of intensive laboratory and clinical research, as indicated by the presentation of over papers at the Sixth International Symposium on Platinum and Other Metal Co-ordination Compounds in Cancer Chemotherapy, held last year.

As the clinical trial data on cisplatin and carboplatin. It is now 20 years since the publication of the anti-tumour activity of platinum compounds by Barnett Rosenberg and his colleagues.

During this time platinum-based drugs have made a major contribution to cancer therapy with significant benefits for many patients. This article summarises the history of platinum agents in this field and indicates the current and possible.

Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat are coordination complexes of drugs are used to treat almost half of people receiving chemotherapy for cancer. In this form of chemotherapy, popular drugs include cisplatin, oxaliplatin, and carboplatin, but several have been proposed or are.

The latter marked a milestone in drug discovery for inorganic complexes, revolutionizing cancer treatment and shifting focus to rational design to improve metal-based drugs, where other. The Second International Symposium on Platinum Coordination Complexes in Cancer Chemotherapy, held at Wadham College, Oxford in April, devoted one day to the results of the first clinical trials of cis Pt II, and so for the first time enabled a preliminary assessment of the likely usefulness of platinum complexes in the clinic.

Light-Activated Destruction of Cancer Cell Nuclei by Platinum Diazide Complexes. The activity of platinum diazide complexes does not rely on the presence of oxygen, which is a potential advantage, as some tumors are oxygen deficient. R.T. DorrPlatinum and Other Metal Coordination Compounds in Cancer by:.

Place and Duration. Six (6) novel rhenium pentycarbanato compounds (PC) were synthesized and triple node negative breast cancer cell lines HTB and Balb/c mouse kidney cell lines were treated with each of them for 48 results were analyzed by a common trypan blue cell death assay system and statistically by: 9.On the other hand, the DNA adducts containing the platinum(II) or platinum(IV) analogues differ in the number of ligands and the formal charge on their platinum center.

We suggest that these dififerences could be responsible for distinct conformational features and stability of DNA modified by platinum(II) or platinum(IV) by: Skip to Article Content; Skip to Article InformationCited by: